Epistasis - Y (wtccc_t2d); I (fastInsulin)
Yanyu Liang
March 06, 2018
Read data
source(paste0(root.dir, "scripts/myRLib.R"))
funcset <- readLines(paste0(root.dir, "output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/sig_subset.set"))
funcset <- parseFuncSet(funcset)
funcset.names <- names(funcset)
xtyi.files <- strsplit("output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e+00.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-01.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-01.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-02.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-02.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-03.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-03.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-04.assoc.logistic:output-direction_XT_YI/fastInsulin__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-04.assoc.logistic",
":")[[1]]
ps <- strsplit("1,0.3,0.1,0.03,0.01,0.003,0.001,0.0003,0.0001",
",")[[1]]
inter.files <- strsplit("output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e+00.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p3.0000e-01.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e-01.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p3.0000e-02.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e-02.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p3.0000e-03.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e-03.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p3.0000e-04.assoc.logistic:output-run_step2/fastInsulin__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e-04.assoc.logistic",
":")[[1]]
prs.files <- strsplit("../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e+00.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-01.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-01.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-02.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-02.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-03.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-03.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-04.txt:../step1/output-run_step1/fastInsulin__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-04.txt",
":")[[1]]Epistasis
for (i in 1:length(xtyi.files)) {
cat("##", funcset.names[i])
cat("
")
cat("
")
snp.subset <- funcset[[funcset.names[i]]]
# read I ~ SNP
prs <- read.table(paste0(root.dir, prs.files[i]), header = T)
prs$sid <- as.character(prs$sid)
prs.sub <- prs[prs$sid %in% snp.subset, ]
# read others
xtyi <- read.table(paste0(root.dir, xtyi.files[i]), header = T)
xtyi$SNP <- as.character(xtyi$SNP)
yt.xtyi <- xtyi[(xtyi$SNP %in% snp.subset) & (xtyi$SNP %in%
prs.sub$sid), ]
yt.xtyi.xt <- yt.xtyi[yt.xtyi$TEST == "ADD", ]
yt.xtyi.yi <- yt.xtyi[yt.xtyi$TEST == "PRS", ]
inter <- read.table(paste0(root.dir, inter.files[i]), header = T)
inter$SNP <- as.character(inter$SNP)
inter <- inter[inter$TEST == "ADDxPRS", ]
yt.inter <- inter[(inter$SNP %in% snp.subset) & (inter$SNP %in%
prs.sub$sid), ]
# order all rows
yt.xtyi.xt <- yt.xtyi.xt[order(yt.xtyi.xt$SNP), ]
yt.xtyi.yi <- yt.xtyi.yi[order(yt.xtyi.yi$SNP), ]
yt.inter <- yt.inter[order(yt.inter$SNP), ]
prs.sub <- prs.sub[order(prs.sub$sid), ]
# check direction
prs.sub$nt1 <- as.character(prs.sub$nt1)
yt.xtyi.xt$A1 <- as.character(yt.xtyi.xt$A1)
yt.inter$A1 <- as.character(yt.inter$A1)
if (sum(prs.sub$nt1 != yt.xtyi.xt$A1) != 0 | sum(prs.sub$nt1 !=
yt.inter$A1) != 0) {
print("Direction does not match. Exit!")
quit()
}
yt.xtyi.xt.mean.std <- getMeanStd(yt.xtyi.xt$SNP, yt.xtyi.xt$P,
yt.xtyi.xt$OR, "Y~Gi+I (Gi)")
yt.xtyi.yi.mean.std <- getMeanStd(yt.xtyi.yi$SNP, yt.xtyi.yi$P,
yt.xtyi.yi$OR, "Y~Gi+I (I)")
yt.inter.mean.std <- getMeanStd(yt.inter$SNP, yt.inter$P,
yt.inter$OR, "Y~Gi*I")
prs.sub.mean.std <- data.frame(SNP = prs.sub$sid, Mean = prs.sub$ldpred_beta,
Std = 0, Type = "I~Gi")
# create data frame for plot
df <- rbind(yt.xtyi.xt.mean.std, yt.xtyi.yi.mean.std, prs.sub.mean.std,
yt.inter.mean.std)
ratio <- max(1, nrow(yt.inter)/40)
cat
p <- ggplot(df) + geom_point(aes(x = SNP, y = Mean)) + geom_errorbar(aes(x = SNP,
ymin = Mean - 1.96 * Std, ymax = Mean + 1.96 * Std),
colour = "black", width = 0.1) + geom_hline(yintercept = 0,
color = "red") + facet_grid(. ~ Type, scales = "free_x") +
coord_flip() + theme(axis.text.x = element_text(angle = 90,
hjust = 1))
p2 <- ggplot(yt.inter) + geom_bar(aes(x = SNP, y = -log10(P)),
stat = "identity") + coord_flip() + ggtitle("Interaction P-value")
subchunkify(p, ratio)
subchunkify(p2, ratio)
cat("
")
inter.plus.gwas.pval <- cbind(yt.inter, yt.xtyi.xt$P)
colnames(inter.plus.gwas.pval) <- c(colnames(yt.inter), "GWAS.P")
pander(inter.plus.gwas.pval[order(inter.plus.gwas.pval$P,
decreasing = F), ])
cat("
")
cat("
")
}p1.0000e+00
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.7585 | -2.578 | 0.009949 | 1.828e-05 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 1.198 | 1.886 | 0.05933 | 3.309e-08 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.8266 | -1.771 | 0.07662 | 2.422e-05 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 1.175 | 1.695 | 0.09009 | 2.894e-08 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.215 | 1.659 | 0.09703 | 4.991e-06 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.8228 | -1.659 | 0.09716 | 9.719e-06 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.8296 | -1.575 | 0.1152 | 2.828e-06 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.187 | 1.37 | 0.1708 | 3.746e-05 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 1.323 | 1.337 | 0.1814 | 3.977e-05 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 1.132 | 1.325 | 0.185 | 3.81e-07 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 1.129 | 1.294 | 0.1957 | 2.76e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 1.129 | 1.294 | 0.1957 | 2.76e-07 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 1.127 | 1.282 | 0.2 | 1.213e-06 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.162 | 1.272 | 0.2035 | 1.671e-06 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.8905 | -1.238 | 0.2156 | 1.296e-05 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.8912 | -1.228 | 0.2195 | 1e-05 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.8892 | -1.189 | 0.2345 | 1.234e-12 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.8792 | -1.185 | 0.2359 | 4.095e-05 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.899 | -1.11 | 0.2671 | 5.027e-11 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.8888 | -1.041 | 0.298 | 1.538e-05 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 0.9079 | -1.003 | 0.316 | 6.648e-11 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.101 | 1.001 | 0.3166 | 3.722e-06 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.11 | 0.9754 | 0.3294 | 8.396e-06 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 0.9106 | -0.9651 | 0.3345 | 1.625e-12 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 0.9133 | -0.9459 | 0.3442 | 4.418e-11 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9128 | -0.944 | 0.3452 | 2.5e-11 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.9024 | -0.8919 | 0.3724 | 1.014e-05 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.089 | 0.8802 | 0.3787 | 9.519e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9037 | -0.879 | 0.3794 | 1.015e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 1.081 | 0.8297 | 0.4067 | 6.138e-06 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.9093 | -0.8245 | 0.4096 | 5.187e-06 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9227 | -0.8131 | 0.4161 | 1.784e-12 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 1.078 | 0.7958 | 0.4262 | 7.408e-06 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9339 | -0.7264 | 0.4676 | 6.356e-06 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 1.068 | 0.6595 | 0.5096 | 6.697e-06 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9412 | -0.6031 | 0.5464 | 1.799e-10 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9447 | -0.5892 | 0.5557 | 9.926e-06 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 0.9494 | -0.5575 | 0.5772 | 2.889e-05 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 0.9187 | -0.5462 | 0.585 | 1.164e-05 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.05 | 0.4921 | 0.6226 | 4.195e-05 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 0.9516 | -0.492 | 0.6227 | 4.27e-06 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.042 | 0.4186 | 0.6755 | 3.324e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 0.9631 | -0.4039 | 0.6863 | 1.479e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 0.9635 | -0.3996 | 0.6894 | 1.571e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 1.033 | 0.3294 | 0.7419 | 2.414e-05 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 1.032 | 0.3179 | 0.7506 | 3.518e-05 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.028 | 0.2735 | 0.7845 | 3.117e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.028 | 0.2735 | 0.7845 | 3.117e-05 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9689 | -0.1985 | 0.8427 | 5.682e-06 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.015 | 0.155 | 0.8769 | 5.052e-05 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.004 | 0.0442 | 0.9647 | 4.128e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.002 | 0.02507 | 0.98 | 8.995e-08 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 0.9992 | -0.008209 | 0.9935 | 3.694e-08 |
p3.0000e-01
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.7904 | -2.251 | 0.02437 | 1.986e-05 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.7997 | -2.132 | 0.033 | 2.524e-05 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 1.186 | 1.829 | 0.06738 | 3.389e-08 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 1.162 | 1.617 | 0.1059 | 2.97e-08 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.201 | 1.603 | 0.1089 | 4.83e-06 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.8339 | -1.587 | 0.1124 | 1.039e-05 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.21 | 1.56 | 0.1188 | 3.612e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.8415 | -1.496 | 0.1347 | 2.987e-06 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 1.336 | 1.417 | 0.1565 | 3.873e-05 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 1.123 | 1.268 | 0.2049 | 3.85e-07 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 1.12 | 1.243 | 0.214 | 2.802e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 1.12 | 1.243 | 0.214 | 2.802e-07 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.153 | 1.242 | 0.2142 | 1.595e-06 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.8787 | -1.226 | 0.2204 | 3.83e-05 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 1.114 | 1.183 | 0.2367 | 1.22e-06 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.8988 | -1.168 | 0.2429 | 1.22e-05 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.8996 | -1.156 | 0.2475 | 9.425e-06 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.8961 | -1.142 | 0.2533 | 9.706e-13 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9006 | -1.118 | 0.2634 | 4.309e-11 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.106 | 1.084 | 0.2785 | 3.804e-06 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.8925 | -1.031 | 0.3025 | 1.615e-05 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 0.9119 | -0.9807 | 0.3267 | 5.665e-11 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 0.9117 | -0.9763 | 0.3289 | 1.386e-12 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 0.9155 | -0.9433 | 0.3455 | 3.702e-11 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.092 | 0.933 | 0.3508 | 9.74e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9039 | -0.9014 | 0.3674 | 1.069e-05 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.904 | -0.8999 | 0.3682 | 1.069e-05 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9194 | -0.8917 | 0.3726 | 2.119e-11 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9217 | -0.8886 | 0.3742 | 6.429e-06 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.093 | 0.8576 | 0.3911 | 7.722e-06 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.911 | -0.8304 | 0.4063 | 5.463e-06 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 1.076 | 0.8006 | 0.4233 | 5.931e-06 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 1.073 | 0.7684 | 0.4422 | 7.169e-06 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 1.072 | 0.7232 | 0.4696 | 6.644e-06 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9341 | -0.708 | 0.479 | 1.425e-12 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 0.9447 | -0.6251 | 0.5319 | 2.776e-05 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9479 | -0.5668 | 0.5708 | 9.834e-06 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 0.9225 | -0.5344 | 0.5931 | 1.229e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 0.9567 | -0.4864 | 0.6267 | 1.511e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 0.9567 | -0.4855 | 0.6273 | 1.42e-05 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9566 | -0.4537 | 0.65 | 1.516e-10 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.04 | 0.4089 | 0.6826 | 4.085e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.038 | 0.3928 | 0.6945 | 5.107e-05 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 0.9648 | -0.3657 | 0.7146 | 4.194e-06 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.029 | 0.3021 | 0.7626 | 3.204e-05 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.029 | 0.2911 | 0.771 | 3.12e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.029 | 0.2911 | 0.771 | 3.12e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 1.026 | 0.2661 | 0.7902 | 2.406e-05 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 1.025 | 0.2592 | 0.7955 | 3.505e-05 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 1.03 | 0.1896 | 0.8497 | 5.709e-06 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 0.9947 | -0.05865 | 0.9532 | 8.335e-08 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 0.9966 | -0.03736 | 0.9702 | 3.346e-08 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.001 | 0.00698 | 0.9944 | 4.109e-05 |
p1.0000e-01
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.7804 | -2.634 | 0.008446 | 2.823e-05 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.211 | 1.752 | 0.07971 | 3.432e-05 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 1.136 | 1.526 | 0.1271 | 3.976e-08 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.8714 | -1.474 | 0.1405 | 2.301e-05 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.158 | 1.428 | 0.1534 | 4.901e-06 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 1.282 | 1.36 | 0.1739 | 3.675e-05 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.8728 | -1.319 | 0.1872 | 1.204e-05 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 1.113 | 1.29 | 0.1972 | 3.503e-08 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.887 | -1.271 | 0.2036 | 3.57e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.8809 | -1.223 | 0.2212 | 3.388e-06 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.104 | 1.191 | 0.2335 | 4.208e-06 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.124 | 1.129 | 0.2589 | 1.576e-06 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.916 | -1.068 | 0.2854 | 7.03e-06 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9167 | -1.036 | 0.3004 | 3.201e-11 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 1.088 | 1.027 | 0.3044 | 4.247e-07 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.9163 | -1.018 | 0.3086 | 5.346e-13 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.089 | 1.015 | 0.3103 | 1.087e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.9203 | -1.01 | 0.3123 | 1.151e-05 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 1.086 | 1.008 | 0.3133 | 3.11e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 1.086 | 1.008 | 0.3133 | 3.11e-07 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.9212 | -0.9975 | 0.3185 | 8.946e-06 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 1.136 | 0.9169 | 0.3592 | 5.631e-06 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.9134 | -0.9167 | 0.3593 | 1.825e-05 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 0.9265 | -0.8985 | 0.3689 | 1.005e-12 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 1.073 | 0.8607 | 0.3894 | 1.361e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.918 | -0.8515 | 0.3945 | 1.216e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.074 | 0.8505 | 0.395 | 4.975e-05 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 0.9313 | -0.8474 | 0.3968 | 2.593e-11 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 0.9313 | -0.8434 | 0.399 | 4.097e-11 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.9208 | -0.8201 | 0.4121 | 1.224e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 0.9378 | -0.7809 | 0.4349 | 2.672e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 1.068 | 0.7616 | 0.4463 | 5.93e-06 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.9275 | -0.7479 | 0.4545 | 6.305e-06 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9435 | -0.6892 | 0.4907 | 1.509e-11 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 0.945 | -0.6877 | 0.4916 | 1.453e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 0.9458 | -0.6771 | 0.4983 | 1.368e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 1.055 | 0.6536 | 0.5134 | 5.797e-06 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 1.052 | 0.6265 | 0.531 | 7.025e-06 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9571 | -0.5097 | 0.6103 | 8.103e-13 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.047 | 0.4892 | 0.6247 | 7.044e-06 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.962 | -0.4562 | 0.6482 | 9.461e-06 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 0.944 | -0.4261 | 0.67 | 1.335e-05 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.031 | 0.3535 | 0.7237 | 3.353e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.031 | 0.3535 | 0.7237 | 3.353e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 0.982 | -0.2243 | 0.8226 | 7.141e-08 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.015 | 0.1714 | 0.8639 | 3.72e-05 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9887 | -0.1299 | 0.8966 | 9.187e-11 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 0.9914 | -0.1057 | 0.9158 | 2.74e-08 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 1.009 | 0.1056 | 0.9159 | 3.402e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 1.009 | 0.1011 | 0.9195 | 2.338e-05 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 0.9918 | -0.0941 | 0.925 | 4.344e-06 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.008 | 0.08849 | 0.9295 | 4.218e-05 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.005 | 0.06124 | 0.9512 | 2.899e-05 |
p3.0000e-02
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.7947 | -2.83 | 0.00465 | 3.248e-05 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.163 | 1.628 | 0.1035 | 3.358e-05 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 1.213 | 1.626 | 0.1039 | 5.605e-06 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.096 | 1.288 | 0.1978 | 4.803e-06 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9029 | -1.255 | 0.2095 | 3.743e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.094 | 1.253 | 0.2101 | 4.49e-05 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.083 | 1.095 | 0.2737 | 1.255e-05 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9282 | -1.055 | 0.2915 | 8.416e-06 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 0.928 | -1.04 | 0.2981 | 2.663e-05 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 1.172 | 1.023 | 0.3065 | 3.473e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 0.9299 | -1.012 | 0.3115 | 1.442e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 0.931 | -0.9945 | 0.32 | 1.368e-05 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.091 | 0.9872 | 0.3236 | 5.74e-06 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 1.065 | 0.8818 | 0.3779 | 5.422e-08 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.9414 | -0.8471 | 0.3969 | 1.165e-05 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.9426 | -0.8283 | 0.4075 | 9.152e-06 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.9289 | -0.8181 | 0.4133 | 1.366e-05 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.074 | 0.8031 | 0.4219 | 1.817e-06 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9451 | -0.7837 | 0.4332 | 2.495e-11 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.9355 | -0.7387 | 0.4601 | 3.812e-06 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.9471 | -0.736 | 0.4617 | 2.634e-13 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 1.049 | 0.6647 | 0.5063 | 4.8e-08 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 1.049 | 0.6451 | 0.5189 | 4.617e-06 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 0.9546 | -0.6397 | 0.5224 | 7.642e-13 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9484 | -0.6113 | 0.541 | 1.382e-05 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.9497 | -0.6066 | 0.5441 | 2.059e-05 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 1.041 | 0.5752 | 0.5651 | 5.207e-07 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 1.041 | 0.5633 | 0.5733 | 3.813e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 1.041 | 0.5633 | 0.5733 | 3.813e-07 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 0.9607 | -0.5572 | 0.5774 | 1.941e-11 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.9533 | -0.5509 | 0.5817 | 1.406e-05 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 0.9633 | -0.518 | 0.6044 | 3.123e-11 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.9583 | -0.4911 | 0.6234 | 7.376e-06 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.034 | 0.4518 | 0.6514 | 3.972e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.034 | 0.4518 | 0.6514 | 3.972e-05 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.9668 | -0.4223 | 0.6728 | 2.518e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 0.9731 | -0.3904 | 0.6962 | 6.199e-08 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.028 | 0.3727 | 0.7094 | 4.585e-05 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 1.024 | 0.3401 | 0.7338 | 1.743e-06 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9762 | -0.3333 | 0.7389 | 1.116e-11 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 1.021 | 0.2817 | 0.7782 | 4.602e-11 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 0.9804 | -0.2728 | 0.785 | 2.576e-05 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 0.9693 | -0.2664 | 0.7899 | 1.359e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 1.019 | 0.2655 | 0.7906 | 6.165e-06 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 1.018 | 0.2493 | 0.8031 | 7.48e-06 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9835 | -0.228 | 0.8197 | 9.116e-06 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.017 | 0.2275 | 0.82 | 4.887e-06 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9841 | -0.217 | 0.8282 | 4.106e-13 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 0.9859 | -0.1936 | 0.8465 | 3.203e-05 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 0.9867 | -0.1905 | 0.8489 | 2.285e-08 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9926 | -0.099 | 0.9211 | 2.212e-05 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 0.9939 | -0.07672 | 0.9388 | 7.475e-06 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9943 | -0.07618 | 0.9393 | 3.215e-05 |
p1.0000e-02
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.8009 | -2.673 | 0.007524 | 3.301e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.121 | 1.562 | 0.1184 | 4.146e-05 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 1.192 | 1.445 | 0.1484 | 5.598e-06 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.14 | 1.396 | 0.1628 | 3.415e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 0.912 | -1.237 | 0.2162 | 1.394e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 0.9129 | -1.222 | 0.2217 | 2.608e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 0.913 | -1.221 | 0.2222 | 1.329e-05 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.092 | 1.197 | 0.2313 | 5.033e-06 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9041 | -1.195 | 0.2321 | 3.985e-05 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.076 | 0.9764 | 0.3289 | 1.308e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.9368 | -0.8844 | 0.3765 | 1.154e-05 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.067 | 0.8492 | 0.3957 | 4.52e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.067 | 0.8492 | 0.3957 | 4.52e-05 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.9394 | -0.846 | 0.3975 | 9.126e-06 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9405 | -0.8423 | 0.3996 | 9.393e-06 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 1.061 | 0.7639 | 0.4449 | 3.556e-11 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.066 | 0.7029 | 0.4821 | 6.752e-06 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.052 | 0.6756 | 0.4993 | 5.184e-05 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.053 | 0.6557 | 0.512 | 5.225e-06 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.061 | 0.647 | 0.5176 | 2.128e-06 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.9464 | -0.5855 | 0.5582 | 1.498e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.9513 | -0.5325 | 0.5944 | 4.231e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9581 | -0.4766 | 0.6337 | 1.514e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 1.035 | 0.461 | 0.6448 | 3.565e-06 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.9624 | -0.4365 | 0.6625 | 2.239e-05 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 0.9687 | -0.4273 | 0.6691 | 2.498e-05 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.9643 | -0.4051 | 0.6854 | 1.547e-05 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 1.028 | 0.3767 | 0.7064 | 1.212e-11 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 0.9745 | -0.3409 | 0.7332 | 2.982e-05 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.9699 | -0.3403 | 0.7336 | 8.242e-06 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 0.9725 | -0.3397 | 0.7341 | 9.059e-06 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 1.053 | 0.3294 | 0.7419 | 3.125e-05 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 1.024 | 0.3125 | 0.7547 | 3.468e-13 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 1.023 | 0.2736 | 0.7844 | 2.412e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9801 | -0.2583 | 0.7962 | 2.118e-05 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 1.019 | 0.2512 | 0.8016 | 6.615e-08 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.016 | 0.2148 | 0.83 | 3.415e-11 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9839 | -0.2085 | 0.8348 | 3.089e-05 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9853 | -0.1983 | 0.8428 | 9.282e-06 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 0.9877 | -0.1717 | 0.8637 | 6.893e-08 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.013 | 0.1705 | 0.8646 | 2.137e-11 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.9872 | -0.1694 | 0.8654 | 2.254e-13 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 1.009 | 0.1294 | 0.897 | 5.831e-07 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9914 | -0.12 | 0.9045 | 2.022e-06 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 1.008 | 0.114 | 0.9092 | 4.266e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 1.008 | 0.114 | 0.9092 | 4.266e-07 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9931 | -0.094 | 0.9251 | 2.772e-11 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 1.006 | 0.0879 | 0.93 | 5.796e-08 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.006 | 0.0806 | 0.9358 | 2.508e-08 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.9947 | -0.07369 | 0.9413 | 7.885e-06 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.9952 | -0.06674 | 0.9468 | 6.492e-06 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.008 | 0.06241 | 0.9502 | 1.241e-05 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.003 | 0.03492 | 0.9721 | 8.531e-13 |
p3.0000e-03
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.8036 | -2.205 | 0.02748 | 2.918e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.175 | 1.829 | 0.06742 | 3.85e-05 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.215 | 1.708 | 0.0876 | 3.483e-05 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.133 | 1.302 | 0.1929 | 5.367e-06 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.126 | 1.296 | 0.195 | 4.792e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.126 | 1.296 | 0.195 | 4.792e-05 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 1.121 | 1.223 | 0.2215 | 4.02e-11 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 1.108 | 1.152 | 0.2494 | 1.725e-11 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 0.9027 | -1.134 | 0.2567 | 1.395e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 0.9026 | -1.134 | 0.2569 | 2.648e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 0.9033 | -1.126 | 0.2603 | 1.324e-05 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.102 | 1.1 | 0.2714 | 4.556e-11 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 1.103 | 1.06 | 0.2893 | 4.741e-13 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.097 | 1.04 | 0.2981 | 2.854e-11 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9021 | -1.002 | 0.3163 | 3.755e-05 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.081 | 0.8761 | 0.381 | 1.215e-12 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.073 | 0.7766 | 0.4374 | 5.564e-05 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.083 | 0.7239 | 0.4691 | 2.217e-06 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.9378 | -0.7217 | 0.4705 | 1.138e-05 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 1.065 | 0.7038 | 0.4816 | 4.071e-11 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.104 | 0.6772 | 0.4983 | 1.025e-05 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9423 | -0.6753 | 0.4995 | 1.025e-05 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9293 | -0.675 | 0.4997 | 1.937e-05 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.06 | 0.6563 | 0.5116 | 5.29e-06 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.9439 | -0.6488 | 0.5164 | 9.05e-06 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.073 | 0.6416 | 0.5211 | 7.087e-06 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 1.06 | 0.6277 | 0.5302 | 3.159e-13 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.9309 | -0.6248 | 0.5321 | 1.903e-05 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.056 | 0.6214 | 0.5343 | 3.239e-08 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 1.093 | 0.6081 | 0.5431 | 4.767e-06 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.9365 | -0.603 | 0.5465 | 1.987e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.9367 | -0.5745 | 0.5656 | 5.517e-06 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 1.058 | 0.571 | 0.568 | 2.174e-05 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.941 | -0.5706 | 0.5683 | 2.823e-05 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9536 | -0.5428 | 0.5872 | 2.235e-06 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 0.9102 | -0.5235 | 0.6007 | 2.833e-05 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.9501 | -0.4701 | 0.6383 | 1.076e-05 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.041 | 0.4438 | 0.6572 | 1.328e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.032 | 0.3615 | 0.7177 | 8.911e-08 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.9692 | -0.3519 | 0.7249 | 6.624e-08 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 1.031 | 0.3405 | 0.7335 | 2.854e-06 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 0.9701 | -0.3405 | 0.7335 | 2.395e-05 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9707 | -0.3378 | 0.7355 | 4.58e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9707 | -0.3378 | 0.7355 | 4.58e-07 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.9708 | -0.3368 | 0.7363 | 8.682e-06 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9706 | -0.3335 | 0.7388 | 9.325e-06 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.969 | -0.3325 | 0.7395 | 1.982e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.9723 | -0.3193 | 0.7495 | 7.131e-06 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9739 | -0.301 | 0.7634 | 6.268e-07 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 0.9775 | -0.2558 | 0.7981 | 7.746e-08 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9767 | -0.2488 | 0.8035 | 2.91e-05 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 0.9797 | -0.2236 | 0.823 | 2.795e-05 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 0.9854 | -0.1483 | 0.8821 | 1.054e-05 |
p1.0000e-03
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.321 | 2.082 | 0.03736 | 3.791e-05 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.7983 | -1.955 | 0.05053 | 2.568e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.22 | 1.92 | 0.05486 | 3.675e-05 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.214 | 1.735 | 0.08275 | 5.47e-06 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 1.165 | 1.484 | 0.1379 | 3.149e-11 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.167 | 1.454 | 0.1458 | 4.782e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.167 | 1.454 | 0.1458 | 4.782e-05 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.161 | 1.45 | 0.1469 | 7.807e-11 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.152 | 1.381 | 0.1673 | 4.891e-11 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 1.159 | 1.36 | 0.1738 | 1.089e-12 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 1.149 | 1.269 | 0.2045 | 7.726e-11 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.137 | 1.244 | 0.2134 | 2.257e-12 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 1.122 | 1.113 | 0.2659 | 7.565e-11 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.213 | 1.112 | 0.2663 | 8.867e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.876 | -1.038 | 0.2991 | 2.381e-05 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 0.8089 | -1.032 | 0.3021 | 2.64e-05 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 1.112 | 0.9808 | 0.3267 | 7.382e-13 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.8836 | -0.9717 | 0.3312 | 2.445e-05 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.104 | 0.9641 | 0.335 | 4.844e-08 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 0.9111 | -0.8878 | 0.3747 | 2.762e-05 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.8948 | -0.8865 | 0.3753 | 3.438e-05 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.8993 | -0.881 | 0.3783 | 3.416e-05 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.8925 | -0.8486 | 0.3961 | 2.316e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 0.9154 | -0.8443 | 0.3985 | 1.445e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 0.9154 | -0.8438 | 0.3988 | 1.363e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.087 | 0.8138 | 0.4158 | 1.286e-07 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.104 | 0.7704 | 0.4411 | 2.142e-06 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.9069 | -0.7665 | 0.4434 | 1.334e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.9033 | -0.7635 | 0.4452 | 6.854e-06 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.073 | 0.6702 | 0.5027 | 6.003e-05 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.089 | 0.669 | 0.5035 | 6.839e-06 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9389 | -0.6186 | 0.5362 | 2.362e-06 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9394 | -0.6106 | 0.5414 | 1.126e-05 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 1.072 | 0.6008 | 0.548 | 1.993e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.9451 | -0.5471 | 0.5843 | 1.147e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9472 | -0.4922 | 0.6226 | 1.91e-05 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9536 | -0.4647 | 0.6421 | 4.975e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9536 | -0.4647 | 0.6421 | 4.975e-07 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.9538 | -0.4579 | 0.647 | 9.144e-06 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.9578 | -0.418 | 0.6759 | 7.254e-08 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9589 | -0.4109 | 0.6811 | 6.788e-07 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 1.043 | 0.401 | 0.6884 | 2.605e-06 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9579 | -0.39 | 0.6965 | 2.827e-05 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9626 | -0.3669 | 0.7137 | 9.181e-06 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 0.9639 | -0.3568 | 0.7213 | 8.671e-08 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.9656 | -0.3412 | 0.733 | 9.417e-06 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 0.9662 | -0.3312 | 0.7405 | 2.259e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.9678 | -0.3193 | 0.7495 | 7.724e-06 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.023 | 0.194 | 0.8462 | 1.134e-05 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.019 | 0.1824 | 0.8552 | 5.579e-06 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9928 | -0.04212 | 0.9664 | 3.91e-06 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 0.9973 | -0.025 | 0.9801 | 2.683e-05 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.001 | 0.009705 | 0.9923 | 1.363e-05 |
p3.0000e-04
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.512 | 2.685 | 0.007257 | 3.955e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.273 | 2.043 | 0.04102 | 3.438e-05 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.7804 | -1.885 | 0.05944 | 2.404e-05 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.251 | 1.772 | 0.07641 | 5.821e-06 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.203 | 1.538 | 0.124 | 4.721e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.203 | 1.538 | 0.124 | 4.721e-05 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.807 | -1.471 | 0.1412 | 2.66e-05 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.8138 | -1.414 | 0.1574 | 2.726e-05 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 1.168 | 1.33 | 0.1834 | 4.2e-11 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 1.174 | 1.302 | 0.1928 | 1.722e-12 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.161 | 1.276 | 0.2019 | 1.02e-10 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.8328 | -1.276 | 0.2019 | 3.802e-05 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 0.7443 | -1.267 | 0.2053 | 2.491e-05 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.151 | 1.211 | 0.2261 | 6.367e-11 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.8443 | -1.16 | 0.246 | 1.486e-05 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.8431 | -1.119 | 0.2632 | 2.571e-05 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.137 | 1.099 | 0.2718 | 3.042e-12 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.137 | 1.092 | 0.2747 | 6.06e-08 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.131 | 1.045 | 0.2959 | 1.529e-07 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 1.129 | 1.035 | 0.3007 | 9.892e-11 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 1.134 | 1.013 | 0.311 | 1.175e-10 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.8626 | -0.9734 | 0.3303 | 7.612e-06 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.208 | 0.9518 | 0.3412 | 8.272e-06 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 1.122 | 0.9321 | 0.3513 | 1.184e-12 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.096 | 0.7628 | 0.4456 | 6.664e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 0.9169 | -0.7338 | 0.4631 | 3.053e-05 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.113 | 0.7321 | 0.4641 | 2.105e-06 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 0.9239 | -0.67 | 0.5029 | 1.515e-05 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9258 | -0.6682 | 0.504 | 2.362e-06 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 1.083 | 0.662 | 0.508 | 2.581e-06 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 0.9255 | -0.655 | 0.5125 | 1.607e-05 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.097 | 0.6383 | 0.5232 | 6.536e-06 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 1.087 | 0.6322 | 0.5273 | 2.003e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9252 | -0.6213 | 0.5344 | 1.94e-05 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.085 | 0.6213 | 0.5344 | 1.145e-05 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 0.9317 | -0.5996 | 0.5487 | 2.173e-05 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9225 | -0.5884 | 0.5563 | 3.237e-05 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9351 | -0.5822 | 0.5604 | 5.224e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9351 | -0.5822 | 0.5604 | 5.224e-07 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9409 | -0.5294 | 0.5966 | 7.066e-07 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9371 | -0.5192 | 0.6036 | 2.89e-05 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.9484 | -0.4563 | 0.6482 | 7.358e-08 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.9497 | -0.4428 | 0.6579 | 1.168e-05 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 0.953 | -0.4138 | 0.679 | 9.025e-08 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9565 | -0.3837 | 0.7012 | 1.157e-05 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.9584 | -0.3634 | 0.7163 | 9.281e-06 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9632 | -0.3174 | 0.7509 | 9.476e-06 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9495 | -0.2668 | 0.7896 | 3.371e-06 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 0.9734 | -0.2257 | 0.8214 | 1.471e-05 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.9793 | -0.179 | 0.8579 | 9.986e-06 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.9808 | -0.1665 | 0.8678 | 8.199e-06 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 0.9901 | -0.08245 | 0.9343 | 2.583e-05 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 0.9927 | -0.06232 | 0.9503 | 6.083e-06 |
p1.0000e-04
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.702 | 2.838 | 0.004541 | 4.036e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.359 | 2.146 | 0.03187 | 3.317e-05 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.7449 | -1.851 | 0.06422 | 2.377e-05 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.312 | 1.782 | 0.07468 | 5.76e-06 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.248 | 1.53 | 0.1259 | 4.579e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.248 | 1.53 | 0.1259 | 4.579e-05 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.767 | -1.508 | 0.1316 | 2.638e-05 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.7748 | -1.45 | 0.147 | 2.701e-05 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.7973 | -1.307 | 0.1913 | 3.803e-05 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 1.207 | 1.27 | 0.2041 | 1.873e-12 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 1.184 | 1.201 | 0.2297 | 4.485e-11 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.81 | -1.195 | 0.232 | 1.461e-05 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.183 | 1.193 | 0.2328 | 1.078e-10 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 0.7211 | -1.163 | 0.245 | 2.471e-05 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.8107 | -1.141 | 0.2537 | 2.574e-05 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.17 | 1.12 | 0.2626 | 6.657e-11 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 1.156 | 1.03 | 0.3032 | 1.034e-10 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.155 | 1.018 | 0.3086 | 6.215e-08 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.154 | 1.012 | 0.3116 | 1.539e-07 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.148 | 0.9827 | 0.3258 | 3.196e-12 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.8388 | -0.96 | 0.337 | 7.672e-06 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 1.145 | 0.917 | 0.3592 | 1.297e-12 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.239 | 0.8914 | 0.3727 | 8.044e-06 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 1.14 | 0.8745 | 0.3818 | 1.319e-10 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.8854 | -0.8075 | 0.4194 | 2.032e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 1.122 | 0.7936 | 0.4274 | 2.677e-06 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.8979 | -0.7146 | 0.4749 | 3.021e-05 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.115 | 0.6869 | 0.4921 | 1.168e-05 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 0.9073 | -0.6832 | 0.4945 | 2.151e-05 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 1.11 | 0.6542 | 0.513 | 1.803e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 0.9124 | -0.6444 | 0.5193 | 3.166e-05 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.098 | 0.6433 | 0.52 | 6.848e-05 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.119 | 0.6392 | 0.5227 | 2.061e-06 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 0.9189 | -0.5949 | 0.5519 | 1.575e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 0.9212 | -0.5777 | 0.5634 | 1.67e-05 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.099 | 0.5397 | 0.5894 | 6.32e-06 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9337 | -0.4948 | 0.6208 | 2.195e-06 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9236 | -0.4793 | 0.6318 | 3.378e-05 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9397 | -0.4462 | 0.6554 | 1.132e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.9393 | -0.4457 | 0.6558 | 1.222e-05 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9419 | -0.4317 | 0.666 | 4.895e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9419 | -0.4317 | 0.666 | 4.895e-07 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9127 | -0.3903 | 0.6963 | 3.151e-06 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.9481 | -0.3793 | 0.7045 | 9.68e-06 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9489 | -0.3791 | 0.7046 | 6.612e-07 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9551 | -0.3218 | 0.7476 | 9.344e-06 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.9594 | -0.2964 | 0.7669 | 6.875e-08 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 0.9641 | -0.2611 | 0.794 | 8.498e-08 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 0.9637 | -0.256 | 0.7979 | 1.463e-05 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.9802 | -0.1419 | 0.8871 | 9.772e-06 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.981 | -0.1362 | 0.8917 | 8.039e-06 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 0.9814 | -0.1324 | 0.8947 | 5.927e-06 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 0.9967 | -0.02241 | 0.9821 | 2.551e-05 |